Testimonials

Stress and Tonic Effect of GinsengGo to Top

Dr. Stephen Fulder, a medical research scientist, carried out with other doctors at Maudsley hospital study to test the adaptogenic theory put forward by Prof. Brekhman that ginseng help to overcome stress. Nurses were given either Korean ginseng or a look-alike inert tablet for the first three days of their switch from day work to night work. After the third night, which is the one that they usually feel the most, they were all tested as to performance, energy, tiredness, ability to sleep during the day, and so on. It turned out that as expected after switching to night work, the nurses showed a considerable drop in alertness, energy, proficiency, activity and ability to work, and they felt poorly. Ginseng restored their performance (more than the inert look-alike) and mood, not all the way back to what it was during normal daytime working, but about half way there. This is only after three days at a small dose of just over 1 gram of good quality Korean ginseng. Dr. Y. S. Chang and his co-workers performed tests on 50 college students who received ginseng powder (7.5 grams per day) for 30 days. The anti-stress effect of ginseng was examined by comparison of the eosinophil counts after the injection of ACTH: the extent of reduction in eosinophil count after the ACTH injection was significantly greater in the test group receiving ginseng than the control. No side effects were observed as well.

Dr. Medvedev of the USSR Academy of Science performed an experiment for the investigation of the immediate effects of Panax ginseng on a group of well-trained audio operators by the use of ginseng extract. This group consisted of 32 men ranging in age from 21 to 23. After they had been tested for accuracy and speed in transmitting telegraphic codes as control data, a double blind study was performed within three days. Eighteen men were administered 30 ml of beverage containing ginseng extract, and the remainder a ginseng-free placebo identical in flavour and appearance, one hour before the test of their abilities. Judging from the data, no significant difference was noticed in the velocity of transmitting codes. But in the 18 men who received ginseng extract, the error rate was only 17% whereas the control group revealed 31 %. Therefore, Panax ginseng was thought to have played a prominent role in promoting efficiency at work.

Dr. Popov of the Central Research Institute, Office of Monopoly, Republic of Korea, reported that ginseng was excellent for the treatment of patients showing such symptoms as fatigue, insomnia, memory impairment and unsatisfactory sexual life commonly encountered in the present polluted and stressful environment. There was a 37-year-old male pianist with long-standing fatigue and reduced power of concentration and refractory insomnia probably due to alcohol addiction or the like. He was tested for six months by a-double blind method using ginseng extract and placebo on his musical performance. By taking the ginseng capsules, he gained more intense plaudits by more than 12%. Prof. Brekhman's study (Head of the Institute of Biologically Active Substances, USSR) revealed that shortening the racing time on a 3,000 meter track was possible for 100 young men who took 3% ginseng tincture one and a half hours before racing, whereas the control group raced the same track in 15 minutes and 26 seconds, longer than the experiment group by 53 seconds. And Dr. Yamata (Japan) reported that nurses and swimmers who were administered Korean ginseng showed more rapid recovery from fatigue than did the control group who took thiamine or glucose.

Let us now understand the dynamics of how the body reacts to stress. The stress could be environmental stress caused by pollution, temperature variations due to changes in weather conditions, noise, etc; viral infection of just pressure due to the fast pace of life in our modem commercial society. Now when a virus attacks the body, an adrenal corticotropical hormone (ACTH) is immediately secreted by the pituitary gland located just beneath the brain to activate the adrenal glands, which is located on each side of the spinal column just above the kidneys. The adrenal glands will in turn yield adrenaline in the blood to activate the body for action against the stress. The sugar level will be increased in the blood stream and the blood pressure will be increased as well. When the viral attack is strong, all the resistance of the body is concentrated to defeat the immediate stress (virus).

Accordingly if the body is put under constant stress whatever the stress may be, then the body is weakened and damage can even be done to our vital organs. The earliest warning signs of an unhealthy stress situation are poor appetite, poor stamina, insomnia, diarrhea, and constipation, poor resistance to colds and flu and even loss of sexual desire. Prolonged stress caused health problems like hypertension, diabetes mellitus, rheumatism, heart problems and even cancer. Numerous studies have demonstrated the effects of ginseng on neuropsychological and physical adaptation "against external environmental changes and various stresses. Ginseng has been shown to be beneficial in maintaining normal physiological functions for a longer period than in the case of the control group. Its normalizing properties help regulate all imbalances caused by stress and for this reason ginseng is said to be restorative. When the body conditions were normalized it enhances the defense mechanism in a state of impaired physical and neuropsychological functions. All this is attributed to ginseng adaptogenic properties.

In 1951, Dr. Chernen'kh of the USSR Academy of Science performed an experiment to determine whether ginseng was effective on work efficiency. He measured the speed accuracy of picking up two specific movable types from a mixture of types in each case. Following one hours work, he administered wild ginseng extract to the 1 its group, cultivated Korean ginseng extract to the 2nd group, glucose to the 3rd group and alcohol to the last group and compared the accuracy of the work of these four groups before and after the administration. He found that mistakes made by the alcohol fed group increased 46% and the glucose fed group 16% but the Korean ginseng administered Group was less and the wild ginseng group was the least. Prof. Petkov established that daily doses of ginseng preparations during 15-45 days increase physical endurance and mental capacity for work, as well as industrial activity. The increase in work efficiency was noted not only during the experiment itself but also for a stated period of time (a month and a half) after the experiment.

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Prof. Petkov and Prof. Brekhman have both remarked in their report, that there is a world of difference between ginseng and other stimulants such as caffeine or amphetamine:

Ginseng is not an excitant. It does not cause feelings of over-excitation, emotional disturbance or agitation.

There is a sedative component in ginseng. Unlike other stimulants, there is no difficulty in sleeping after taking it. -Ginseng acts in a stabilizing fashion. The more tired one is, the more noticeable the action. -Ginseng causes an increase in health, appetite and mental condition, especially if taken over a period. The other stimulants cause more ill health the longer they are taken.

Ginseng is much safer.

Ginseng assists in combating stress, while other stimulants can actually cause stress.

Hypertension is a common occurrence after the age of 40. Hypertension still causes about 12% of deaths, and approximately 20% of the world population suffers from hypertension.

Cardiac activity, vascular resistance and blood flow primarily determine blood pressure. It is generally believed that hypertension is due to the demands of modern lifestyle, which is basically stress.

Prof. Takagi conducted study of active ginseng components which counter-balance high and low blood pressure: water-extract-dialysate elevated whereas the undialysable butanol extract lowered it.

Prof. Lee reported that ginseng relieved hypertension by relaxing the smooth muscle of blood vessels.

Prof. Popov reported good results in the management of atherosclerosis with ginseng. He administered ginseng to a group of atherosclerosis patients with cholesterol levels of 280 to 310mg%, which dropped to the normal range with ginseng. He also reported a 56-year-old male patient that was suffering from bilateral cryptochism, azoospermia, mild diabetes mellitus with refractory hypertension and myocardial infarction, which has been persistent for 8 years. The serum cholesterol level was 325 to 375 mg%, which persisted even with various treatments. With ginseng administered twice a day for two weeks, and then once a day afterward without any medication, his blood pressure returned to the normal range and serum cholesterol level fell to 225mg% with the disappearance of glucosuria, and later he could enjoy a normal life without recurrence.

When Korean ginseng is administered to anemic patients, it has been report that subjective symptoms such as unpleasant dizziness, poor appetite, arthritis, thirst, palpitation and heavy feeling are gradually alleviated, even in patients in whom no appreciable decrease in anemia is observed. Particularly, the effects of ginseng in improving appetite suggest that ginseng strengthens the gastrointestinal functions. It is known that presently available blood making drugs for anemic patients frequently impair the gastrointestinal tract and cause various side effects. This was reported by Dr.S. Arichi in his paper" Clinical Application Of Panax Ginseng". Dr. T. Hisayama and his co-workers in their paper" Clinical Experience In The Treatment Of Advance Cancer With Ginsenosides" found that ginsenosides administration provide a restorative effect on leukocyte counts and the hemoglobin level of cancer patients exposed to large dose of radiation. Patients recovered from anemia, leucopoenia and lymphopenia.

Dr. H. Kaneko and his co-workers found that ginseng improved hematodynamics in 16 healthy adults. Ginseng decreased total peripheral resistance, increased stroke volume and myocardial contractility, and lowered systolic and diastolic blood pressure and mean arterial pressure. Ginseng also improved myocardial pumping efficiency and economized myocardial oxygen utilization.

Diabetes mellitus syndrome is caused by impaired glucose metabolism. Pancreatic.Beta cells produce insulin, which transports the glucose into the intracellular compartments and provides an energy source. Accordingly, the deficient production of insulin due to impaired pancreatic beta cells would produce a hyperglycemic syndrome, which consist of glucosuria, polyuria and thirst.

Diabetes mellitus develops in approximately 1-2% of the world population and about 10% of people over 40 years old are said to suffer from diabetes mellitus.

Panax ginseng was administered to 20 diabetic patients (17 males and 13 females) and one diabetic patient with retinal disease. The ginseng reduced the insulin requirement in some patients and also showed improvement in the general physical conditions of the diabetic patient with retinal disease. Subjective symptoms such as languor, fatigue and stiff shoulder were improved and blood pressure normalized. And no side effects from ginseng administration were observed. This report was made by Dr. Y. Yoshita in his report "Ginseng on the treatment of diabetic patients 1982".

Dr. Ryoichi Yoshida, Director of the city general hospital of Ehime, Japan, conducted his study on 21 patients suffering from diabetes mellitus. 2.7gms of ginseng was orally administered for three months and the following are the results reported: 3 patients were greatly improved so that they do not need insulin injections any longer. 5 patients were so improved that the amount of insulin injections could be considered reduced. Diabetic inflammation was reduced in 2 patients. General symptoms such as hypertension and stiff shoulders usually appearing in diabetic patients were appreciably reduced in 2 patients.

These clinical results suggested that 12 out of 21 patients (50%) were improved by the use of ginseng.

Prof. Okuda expressed his opinion about what is called insulin-like substance obtained from Korean ginseng as follows:

1. It seemed not to act simply as insulin but it might act to control the secretion of hormones which are intimately related to sugar and lipid metabolism, leading to the normalization of various metabolic functions in diabetic patients.

2. This means that an insulin-like substance may act on the lower part of the cerebral thalamus, which controls the secretion balance of insulin and anti-insulin hormones through the central nervous system.

3. In other words, the insulin-like substance seems to act as an unknown regulator.

Dr. Murata and Dr. Hirono used prostisol (Korean ginseng component), one of the stimulants of protein synthesis for the treatment of anemia in cancer patients solely or in combination with antineoplastic drugs. They administered prostisol to 43 patients with cancers of various organs. The 43 men were treated for more than three months and they were found to have lymph node metastasis and radical treatment seemed impossible, so they were given prostisol with antineoplastic drugs for six months, and then, the prostisol only.

As a result, 30 cases of 43 patients (70%) showed some clinical improvement and in nine patients there was no recurrence for more than one year. Considerable prolongation of survival time was noticed in six other patients even though they expired during treatment.

On these clinical investigations, Dr. Murata and Dr. Hirano concluded that prostisol seemed to be implicated in the immunologic mechanism and reticulo-endothelial system, and would suppress the neoplastic process by way of increased resistance of the organism without adverse effects. The non-specific increase in resistance of the organism was found to be an important mechanism of ginseng in helping cancer patients.

Summary of Dr. Murata Findings:

1. Korean ginseng stimulates one's appetite, and therefore his or her physical strength develops and clinical improvement will be appreciable.

2. Korean ginseng increases the number of red blood cells and blood pigments, leading to the reduction of anemia in cancer patients.

3. Korean ginseng increases the number of white blood cells, particularly lymphocytes, leading to an increase in the capacity of the body to resist various diseases.

4. Korean ginseng has an immunological effect against cancer as it stimulates the production of immune globulin.

5. Some unknown component of Korean ginseng might function directly against neoplastic tumors.

Dr. Okuda reported that Korean ginseng contains active components, which inhibits the action of cancerous toxin, isolated from the ascitic fluid of cancer patients, which causes cachexia. Dr. I. Murata and Dr. Hirono reported that ginseng saponin administered orally for 30 days to breast cancer patients suffering from a high fever induced by radiation overdose was found to improve on the adverse effects of radiation therapy.

The liver is the largest organ weighing at 1.Skg. In the liver, various intermediary metabolisms occur and it provides the other organs with direct usable energy sources transformed from nutritional substances absorbed from the intestinal tract. Excess energy is stored in the form hepatic glycogen, which is available as an energy source when energy requirement is great. The liver is the site of active lipid metabolism and plays an essential role in the digesting and absorption of fat from food substances in the small intestine in which cholic acids, synthesized in the liver are secreted.

Studies have indicated that ginseng is believed to exert defensive action against many hepatotoxic drugs and agents by the way of increased metabolic enzymes. In addition, ginseng produces a considerable effect on hepatic regeneration and functional recovery of injured livers.

Dr. Koo observed that a commonly used hepatitis remedy supplemented with ginseng promoted the treatment of acute viral hepatitis.

Prof. Brekhman administered Korean ginseng to 44 patients who had showed refractory impotence to all medication for two to five years and observed complete recoveries of 21 patients and considerable improvements of 11 patients.

Dr. Popov and his co-workers administered ginseng to 27 impotent patients, of whom 15 completely recovered and 9 showed considerable improvement.

Impotence and decreased libido are extremely frequent in diabetic patients. Dr. Kakiwoochi reported that Panax ginseng was shown to be effective in the management of the above complications in diabetic patients, and made considerable improvement in 80% of impotent patients and 60% of decreased-libido patients.

Dr. Zhuo studied ginseng anti-aging effects and he demonstrated that ginseng retards cell degeneration, promoted cellular proliferation, improves general health problems related to aging, and thus delays the aging process. His conclusions are that ginseng exerts beneficial effects on the immune system by increasing resistance to the degenerative system and by stimulating metabolic process and cell proliferation.

A simple understanding of the classification of herbs in the Chinese traditional medicine would explain the position of ginseng in terms of toxicity. Ginseng belongs to the 1st class of herbs that exhibit mild reactions and this Kingly category means that it can be taken by healthy as well as those who are sick to aid recovery and smoothen the side-effects of specific drugs. The long history of ginseng and the prescription of ginseng together with other herbs to help normalize the harsh effects of these herbs, should assure all those concerned of over-dosage and toxicity.

Dr. Soldati made the following report on the toxicity of ginseng. Neither teratogenic action, nor adverse effects on fertility, nor carcinogenic effects were observed. No harmful effects on sex hormones or on the cardiovascular system were observed. These results indicate that Panax ginseng may be used with no harmful effect even in long-term administration.

Clinical studies made by Dr. Chang and his associates indicated that ginseng help in the post-operational recovery in 120 gynecologically laparotomized patients. The extent of the elevation of the serum cholesterol level was significantly lower in patients receiving ginseng, and the total serum protein level was higher in the ginseng treated group than in control.

Dr. C. K. Rim and his co-workers showed that ginseng saponin was absorbed into hair 3 times more efficiently than collagen hydrolysate and thus increased its tensile strength and elongation.

The strange fact is that although many doctors still do no think much of herbs and herbalism, large numbers of synthetic medicines used by doctors are originally derived from plants. The medicines may have been extracted, altered and re-synthesized for the purpose of standardization and so on, often the original discovery and isolation of the drug was made through traditional herbs.

As one eminent British scientist said about ginseng, "It is no use doing any research on it until we know what it contains". This attitude is precisely that which prevents western medical experts from understanding and utilizing the wealth of traditional medicines. Who cares what chemicals are inside the plant, as long as it works safely? Besides, ignoring some important medicines, which happen to be too complicated to yield, known active ingredients, there is a more serious danger. The process of extracting and defining active principle may leave out other constituents, which are present in the plant and are important for a balanced treatment. The herbalist understands that herbs work not just from active ingredients but the combined effects in total. Extraction of only the active component (practice of medicine today) is not only unnecessary but may even be harmful which is the case for most drugs.

Ginseng Home Business

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* I moved to Canada in 1996, and had continued my international import and export business.''

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
* Results may not be typical. Your results may vary. Some of the content in this page is from members.tripod.com/~contin/gin04.htm and bing han website